The CryoEM Revolution: Advanced Computational Techniques in Structural Biology: NVIDIA GTC 2021

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Use of GPUs in support of scientific research has a long history. A new generation of cards are now routinely utilized in support of cryo-electron microscopy, protein folding experiments, and genomic analysis, which places unique demand on the infrastructure including storage.

In this session, Dr. Piotr Sliz, Chief Research Information Officer at Boston Children's Hospital and Associate Professor of Biological Chemistry & Molecular Pharmacology and Pediatrics at Harvard Medical School, will provide an overview of two initiatives that integrate advanced analytics environments at the Harvard-based global structural biology SBGrid Consortium and Boston Children’s Hospital Rare Disease Cohorts Initiative.

This environment supported two recently completed scientific projects: a structure determination of SARS-CoV-2 spike protein variant and investigation of genetic susceptibility to multi-system inflammatory syndrome (MIS-C).

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